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Neuroendocrine tumor of the liver in pregnancy: A very rare case report.

Ramya LasmiRamandeep BansalVanita SuriChandan Krushna DasReetu Kundu
Published in: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics (2024)
Neuroendocrine neoplasms (NENs) of the liver represent a rare entity. Amongst this group of uncommon diseases primary hepatic neuroendocrine neoplasm (PH-NEN) represent only 0.3% of all NENs. Moreover, PH-NEN has very rarely been reported in pregnancy. We report a 28-year-old young patient with metastatic small cell neuroendocrine carcinoma of the liver complicated with pregnancy. She was evaluated and managed through a multidisciplinary team approach and received two cycles of chemotherapy with a cisplatin/etoposide regimen during the antenatal period and delivered at 37 weeks period of gestation (POG). This case highlights the importance of major challenges faced during the diagnosis and management of this very rare disease in pregnancy and the successful fetomaternal outcome.
Keyphrases
  • preterm birth
  • case report
  • pregnancy outcomes
  • gestational age
  • squamous cell carcinoma
  • small cell lung cancer
  • stem cells
  • palliative care
  • quality improvement
  • preterm infants
  • cell therapy