Frequency of Hereditary and GBA1-Related Parkinsonism in Latin America: A Systematic Review and Meta-Analysis.

Paula Saffie-Awad Daniel Teixeira Dos Santos Bruno Lopes Dos Santos-Lobato Sarah Teixeira Camargos Mario R Cornejo-Olivas Carlos Roberto de Mello Rieder Ignacio Fernandez Mata Pedro Chaná-Cuevas Christine Klein Artur Francisco Schumacher-Schuh

Published in: Movement disorders : official journal of the Movement Disorder Society (2023)

This study provides insights into hereditary and GBA1-related parkinsonism in Latin America. Lower GBA1 frequencies compared to European/North American cohorts may result from limited access to gene sequencing. Further research is vital for regional prevalence understanding, enabling personalized care and therapies. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Keyphrases

drug induced
parkinson disease
healthcare
palliative care
risk factors
copy number
genome wide
gene expression
systematic review
pain management
chronic pain
transcription factor