Objective Response Rate is a Surrogate Marker for Long-Term Overall Survival in Metastatic Urothelial Carcinoma Patients Treated With Immune Checkpoint Inhibitors.

Deniz TuralCagatay ArslanFatih SelcukbiricikOmer Fatih OlmezMustafa ErmanYüksel ÜrünDilek ErdemSaadettin Kilickap

Published in: Clinical genitourinary cancer (2024)

In conclusion, this 5-year analysis of real-world data in the setting of metastatic urothelial cancer indicated a significant correlation between ORR, especially CR, and OS in patients who received ICIs. Therefore, identifying a potential surrogate marker for survival in patients treated with ICIs would represent an important advance in the early identification of patients' response or resistance to ICIs.

Keyphrases

squamous cell carcinoma
small cell lung cancer
end stage renal disease
newly diagnosed
papillary thyroid
prognostic factors
peritoneal dialysis
free survival
machine learning
risk assessment
squamous cell
lymph node metastasis
climate change
bioinformatics analysis