Changes in Seizure Frequency and Antiepileptic Therapy during Pregnancy.
Page B PennellJacqueline A FrenchRyan C MayElizabeth GerardLaura KalayjianPatricia PenovichEvan GedzelmanJennifer CavittSean T HwangAlison M PackMaria SamJohn W MillerSteffanie H WilsonCarrie BrownAngela K BirnbaumKimford J Meadornull nullPublished in: The New England journal of medicine (2021)
Among women with epilepsy, the percentage who had a higher incidence of seizures during pregnancy than during the postpartum period was similar to that in women who were not pregnant during the corresponding epochs. Changes in doses of antiepileptic drugs occurred more frequently in pregnant women than in nonpregnant women during similar time periods. (Funded by the National Institutes of Health; MONEAD ClinicalTrials.gov number, NCT01730170.).