Homogeneous voltammetric sensing strategy for lead ions based on aptamer gated methylthionine chloride@UiO-66-NH 2 framework as smart target-stimulated responsive nanomaterial.

Herein an innovative electrochemical method is proposed for the determination of lead ions (Pb 2+ ) based on a homogeneous voltammetric (HVC) sensing strategy using an aptamer gated methylthionine chloride@UiO-66-NH 2 framework as a smart target-stimulated responsive material. The proposed HVC sensor exhibits excellent sensing performance: ultralow detection limit (0.166 pM) and wide linearity (5.0 pM-500.0 nM), simultaneously, it avoids electrodeposition processes and it is simple to modify the electrode compared to previous electrochemical methods for Pb 2+ detection. Thus our method shows great potential in the highly efficient detection of Pb 2+ and other heavy metal ions by simply altering the related specific aptamer.