Histone H3 Lysine 4 and 27 Trimethylation Landscape of Human Alzheimer's Disease.

Giuseppe PersicoFrancesca Casciaro Stefano Amatori Martina Rusin Francesco CantatoreAmalia PernaLavinia Alberi Auber Mirco FanelliMarco Giorgio

Published in: Cells (2022)

The signatures of H3K4me3 and H3K27me3 identified in AD patients validate the role of epigenetic chromatin remodeling in neurodegenerative disease and shed light on the genomic adaptive mechanisms involved in AD.

Keyphrases

end stage renal disease
gene expression
endothelial cells
ejection fraction
newly diagnosed
chronic kidney disease
genome wide
dna methylation
dna damage
peritoneal dialysis
prognostic factors
cognitive decline
copy number
patient reported outcomes
patient reported