Sequential combination of Sonic Hedgehog inhibitors followed by consolidation radiotherapy in locally advanced basal cell carcinoma.

Marie Boileau Manon Dubois Clément PruvotEve DesmedtCarole TemplierNicolas MeyerXavier Mirabel Laurent Mortier

Published in: Clinical and experimental dermatology (2024)

SHHi treatment followed by RT consolidation after drug discontinuation seems effective and safe. Further studies are needed to develop a precise strategy for the management of laBCCs.

Keyphrases

locally advanced
basal cell carcinoma
rectal cancer
neoadjuvant chemotherapy
squamous cell carcinoma
radiation therapy
early stage
phase ii study
radiation induced
combination therapy
study protocol