Cu(II)/PTABS-Promoted, Chemoselective Amination of HaloPyrimidines.

Vikram PhulwaleHarshita ShetKrishna Chaitanya GunturuSmruti Rekha RoutRambabu DandelaSuyog AdhavAnant R Kapdi

Published in: The Journal of organic chemistry (2024)

Chemoselective amination is a highly desired synthetic methodology, given its importance as a possible strategy to synthesize various drug molecules and agrochemicals. We, herein, disclose a highly chemoselective Cu(II)-PTABS-promoted amination of pyrimidine structural feature containing different halogen atoms.

Keyphrases

machine learning
aqueous solution
metal organic framework
deep learning
emergency department
drug induced