Circulating CD4+ FoxP3- CXCR5- CXCR3+ PD-1hi cells are elevated in active rheumatoid arthritis and reflect the severity of the disease.

Lei ZhaoZhenxue LiXingyue ZengChangsheng XiaLijuan XuQinzhu XuYing SongChen Liu

Published in: International journal of rheumatic diseases (2021)

Circulating CD4+ FoxP3- CXCR5- CXCR3+ PD-1hi cells in patients with active RA are increased and could reflect the severity of the disease, which may play a potential role in the pathogenesis of RA.

Keyphrases

rheumatoid arthritis
induced apoptosis
cell cycle arrest
regulatory t cells
disease activity
cell migration
ankylosing spondylitis
endoplasmic reticulum stress
cell death
cell proliferation