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Polymorphism but not methylation status in the vitamin D receptor gene contributes to oral mucositis in children.

José Maria Chagas Viana FilhoBeatriz Fernandes de SouzaMarina de Castro CoêlhoAna Maria Gondim ValençaDarlene Camati PersuhnNaila Francis Paulo de Oliveira
Published in: Oral diseases (2022)
OM is associated with lower leukocyte and platelet counts. SOM is associated with the rs1544410 and rs2228570 polymorphisms. The methylation status of the VDR is not associated with inflammation or exposure to MTX®.
Keyphrases
  • genome wide
  • dna methylation
  • oxidative stress
  • peripheral blood
  • young adults
  • copy number
  • radiation induced
  • radiation therapy