Perfusion of the placenta assessed using arterial spin labeling and ferumoxytol dynamic contrast enhanced magnetic resonance imaging in the rhesus macaque.
Kevin W EliceiriSean B FainSydney M NguyenThaddeus G GolosScott B ReederIan M BirdDinesh M ShahOliver E WiebenKevin M JohnsonPublished in: Magnetic resonance in medicine (2018)
The ASL-FAIR and ferumoxytol DCE-MRI methods are feasible to detect early blood delivery to the macaque placenta. Outer volume saturation reduced the high macrovascular ASL signal. Interleukin-1β exposure did not alter placental intervillous perfusion. An endogenous-labeling perfusion technique is limited due to extended transit times for flow within the placenta beyond the immediate vicinity of the maternal spiral arteries.