Impact of Analytical Treatment Interruption on Burden and Diversification of HIV Peripheral Reservoir: A Pilot Study.

Rossana ScutariValentino CostabileLaura GalliMaria Concetta BellocchiLuca CariotiSilvia BarbalisciaAndrea PoliAndrea GalliCarlo Federico PernoMaria-Mercedes SantoroAntonella CastagnaFrancesca Ceccherini-SilbersteinClaudia AlteriVincenzo Spagnuolo

Published in: Viruses (2021)

This pilot study indicates that short ATI does not alter peripheral-total HIV-DNA burden and residual viremia, but in some cases could cause a genetic diversification of peripheral viral reservoir in term of both MRMs rearrangement and viral evolution.

Keyphrases

antiretroviral therapy
hiv positive
hiv infected
hiv testing
human immunodeficiency virus
hepatitis c virus
sars cov
chemotherapy induced
hiv aids
men who have sex with men
circulating tumor
risk factors
cell free
combination therapy
liquid chromatography
gene expression
dna methylation
preterm birth