DNA methylation biomarkers accurately detect esophageal cancer prior and post neoadjuvant chemoradiation.

Catarina Macedo-SilvaVera ConstâncioVera Miranda-GonçalvesPedro Leite-SilvaSofia SaltaJoão LoboRita GuimarãesCarina Carvalho-MaiaDavide GiglianoMónica FarinhaOlga SousaRui HenriqueCarmen Jerónimo

Published in: Cancer medicine (2023)

Overall, our results encourage the use of miRNA methylation biomarkers as accurate ECa detection tools as a novel approach for ChRT response monitoring.

Keyphrases

dna methylation
rectal cancer
locally advanced
genome wide
gene expression
lymph node
high resolution
loop mediated isothermal amplification
radiation therapy
label free
mass spectrometry