Causal relationship between multiple sclerosis and cortical structure: a Mendelian randomization study.

Dongren SunRui WangQin DuYing ZhangHongxi ChenZiyan ShiXiaofei WangHongyu Zhou

Published in: Journal of translational medicine (2024)

Our results provide evidence supporting a causal relationship between MS and cortical structure. Enrichment analysis suggests that the pathways mediating brain morphology abnormalities in MS patients are mainly related to immune and inflammation-driven pathways.

Keyphrases

multiple sclerosis
end stage renal disease
mass spectrometry
white matter
ms ms
newly diagnosed
chronic kidney disease
oxidative stress
prognostic factors
resting state
functional connectivity