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Sinus Node Dysfunction and Pulmonary Hypertension-"Double Trouble" with Lithium Therapy.

Shweta VohraAkshyaya PradhanRishi SethiMonika Bhandari
Published in: The International journal of angiology : official publication of the International College of Angiology, Inc (2021)
Lithium is considered a gold standard drug for the management of bipolar disorder and is a widely used mood-stabilizing drug in psychiatry practice. However, its side effects are of important concern. The narrow therapeutic index of lithium predispose to its toxicity/side effects, but various case reports and research has shown that adverse drug reactions can occur even in the therapeutic range. We present the case of a 56-year-old woman with no history of cardiac illness presenting with tachycardia-bradycardia syndrome along with moderate pulmonary hypertension. Patients recovered to sinus rhythm after withholding lithium therapy for 1 week while her mean pulmonary artery pressure remained the same at day 10 of drug withdrawal.
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