Meningococcal Serogroup ACWYX Conjugate Vaccine in Malian Toddlers.
Milagritos D TapiaSamba O SowAbdi NaficyFatoumata DialloFadima C HaidaraAmol ChaudhariLionel MartelletAwa TraoreKelly Townsend-PayneRay BorrowNancy HoskenIgor SmolenovSambhaji S PisalF Marc LaForceRajeev M DhereDhananjay KapseYuxiao TangMark R AldersonPrasad S KulkarniPublished in: The New England journal of medicine (2021)
No safety concerns were identified with two doses of NmCV-5. A single dose of NmCV-5 elicited immune responses that were similar to those observed with two doses of MenACWY-D. Adjuvanted NmCV-5 provided no discernible benefit over nonadjuvanted NmCV-5. (Funded by the U.K. Foreign, Commonwealth, and Development Office; ClinicalTrials.gov number, NCT03295318.).