Gemcitabine, dexamethasone and cisplatin (GDP) is an effective and well-tolerated mobilization regimen for relapsed and refractory lymphoma: a single center experience
Hikmettullah BatgiBaşcı SemihMehmet Sinan DalMerih Kızıl ÇakarBahar Uncu UluTuğçe Nur YiğenoğluNurgül ÖzcanAli KılınçAlparslan MerdinJale YıldızMehmet BakırtaşDerya ŞahinTahir DarçınDicle İskenderNuran Ahü BaysalFevzi AltuntaşPublished in: Turkish journal of medical sciences (2021)
We suggest that GDP/R-GDP plus G-CSF can be used as an effective chemotherapy regimen for mobilizing CD34+ stem cells from peripheral blood in relapsed and refractory lymphoma patients due to low toxicity, effective tumor reduction, and successful stem cell mobilization. It can also be assumed that the GDP mobilization regimen may be more effective, especially in patients with early-stage disease and in HL patients.
Keyphrases
- end stage renal disease
- stem cells
- early stage
- diffuse large b cell lymphoma
- newly diagnosed
- ejection fraction
- peripheral blood
- chronic kidney disease
- acute lymphoblastic leukemia
- acute myeloid leukemia
- peritoneal dialysis
- squamous cell carcinoma
- multiple myeloma
- mesenchymal stem cells
- oxidative stress
- locally advanced
- high dose
- lymph node
- hodgkin lymphoma
- cell therapy
- sentinel lymph node
- neoadjuvant chemotherapy
- cerebrospinal fluid