EGFR-mutated lung cancer as a secondary neoplasm in a patient with Li-Fraumeni syndrome: case report.
Daniela Cristina Cortés ValenzuelaPablo Andrés Vega MedinaFrancisco José Palma GarcíaOmar Orlando Castillo FernandezPublished in: AME case reports (2024)
and lung cancer with EGFR mutation has been suggested in case reports. Studies in lung cancer cell lines have shown a link between TP53 mutation and EGFR overexpression. Nonetheless, as more cases are reported, further research is needed to comprehend the interrelation between these two pathologies and the risk posed by LFS to the emergence of EGFR-mutated lung cancer.