Login / Signup

Cancer Stem Cells Persist Despite Cellular Damage, Emergence of the Refractory Cell Population.

Ayumi NagaeNorikatsu MiyoshiShiki FujinoMasafumi HorieShinichi YachidaMasaru SasakiYuki SekidoTsuyoshi HataAtsushi HamabeTakayuki OginoHidekazu TakahashiMamoru UemuraHirofumi YamamotoYuichiro DokiHidetoshi Eguchi
Published in: Annals of surgical oncology (2023)
POU5F1 is involved in chemotherapy resistance in relation to stemness. For the treatment against refractory tumors, such as the recurrence after chemotherapy, the treatment should target the emerging specific population such as CD44 (or CD44v9) and proliferative cancer cells.
Keyphrases
  • cancer stem cells
  • stem cells
  • locally advanced
  • oxidative stress
  • single cell
  • epithelial mesenchymal transition
  • cell therapy
  • bone marrow
  • combination therapy
  • rectal cancer
  • mesenchymal stem cells
  • smoking cessation