Immunostimulatory effects of Hsp70 fragments and Hsp27 in design of novel HIV-1 vaccine formulations.

Alireza MilaniElahe AkbariParisa Moradi PordanjaniFateme JamshidiShahrzad GhayoumiSeyed Amir SadeghiAzam Bolhassani

Published in: HIV medicine (2023)

Altogether, these findings demonstrate the significance of Hsps as enhancers of antigen-specific immunity. Notably, the C-Hsp70 region showed better adjuvant properties for inducing cellular immunity in the improvement of HIV-1 therapeutic vaccines.

Keyphrases

heat shock
heat shock protein
antiretroviral therapy
hiv positive
heat stress
hiv testing
hiv infected
human immunodeficiency virus
hepatitis c virus
hiv aids
men who have sex with men
south africa
oxidative stress