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Hierarchicell: an R-package for estimating power for tests of differential expression with single-cell data.

Kip D ZimmermanCarl D Langefeld
Published in: BMC genomics (2021)
Hierarchicell is a user-friendly R-package that provides accurate estimates of power for testing hypotheses of differential expression in single-cell RNA-seq data. This R-package represents an important addition to single-cell RNA analytic tools and will help researchers design experiments with appropriate and accurate power, increasing discovery and improving robustness and reproducibility.
Keyphrases
  • single cell
  • rna seq
  • high throughput
  • electronic health record
  • big data
  • high resolution
  • low cost
  • deep learning