Coronary artery calcification and aortic valve calcification in patients with kidney failure: a sex-disaggregated study.
Liam J WardAgne Laucyte-CibulskieneLeah HernandezJonaz Ripswedennull nullPeter StenvinkelKarolina KublickienePublished in: Biology of sex differences (2023)
In female KF patients inflammatory burden and oxidative stress were associated with CAC. Whereas in male KF patients oxidative stress and inflammation were associated with CAC and AVC, respectively. Our findings suggest a sex-specific biomarker signature for cardiovascular calcification that may affect the development of cardiovascular complications in males and females with KF.
Keyphrases
- oxidative stress
- end stage renal disease
- chronic kidney disease
- aortic valve
- coronary artery
- ejection fraction
- newly diagnosed
- peritoneal dialysis
- prognostic factors
- transcatheter aortic valve replacement
- risk factors
- aortic stenosis
- dna damage
- patient reported outcomes
- transcatheter aortic valve implantation
- induced apoptosis
- left ventricular
- coronary artery disease
- signaling pathway
- pulmonary hypertension
- pulmonary arterial hypertension