Peripheral inflammatory markers associated with brain volume reduction in patients with bipolar I disorder.
Shang-Ying TsaiMartha SajatovicJung-Lung HsuKuo-Hsuan ChungPao-Huan ChenYu-Jui HuangPublished in: Acta neuropsychiatrica (2021)
The volume of brain regions known to be relevant to BD-I may be diminished in relation to higher plasma level of YKL-40, sTNF-R1, and more lifetime mood episodes. Macrophage and macrophage-like cells may be involved in brain volume reduction among BD-I patients.