Influence of daily versus alternate-day dosing of vonoprazan on intragastric pH, serum gastrin, and the antiplatelet function of clopidogrel : Influence of alternate-day dosing of vonoprazan.
Tomohiro HiguchiMihoko YamadeSatoru TakahashiSatoshi TamuraShinya TaniTakuma KagamiTakahiro UotaniYasushi HamayaMoriya IwaizumiSatoshi OsawaKen SugimotoTakahisa FurutaPublished in: European journal of clinical pharmacology (2022)
Alternate-day administration of vonoprazan could not prevent the interaction between vonoprazan and clopidogrel, and acid inhibition was inferior to that with vonoprazan daily administration. Alternate-day administration of vonoprazan thus appears to be of questionable clinical utility.