Obesity is associated with severe clinical course in children with Henoch-Schonlein purpura.
Hatice Adiguzel DundarMehmet PektancMeral Torun BayramAlper SoyluSalih KavukcuPublished in: Pediatric nephrology (Berlin, Germany) (2020)
Obese children with HSP had higher erythrocyte sedimentation rate, hypertension, and severe renal involvement; showed delayed improvement of skin, joint, and kidney findings; and need more immunosuppressive medications and a longer period of steroid treatment. These findings may be associated with the effect of adipose tissue on inflammation.