Faecal metabolite deficit, gut inflammation and diet in Parkinson's disease: Integrative analysis indicates inflammatory response syndrome.
Aisha AugustinAdrien Le GuennecChianna UmamahesanAidan Kendler-RhodesRosalind M TuckerElena ChekmenevaPanteleimon TakisMatthew LewisKarthik BalasubramanianNeville DeSouzaBenjamin Harvey MullishDavid TaylorSuzanne RyanKevin WhelanYun MaMohammad A A IbrahimIngvar BjarnasonBu' Hussain HayeeAndré CharlettSylvia M DobbsR John DobbsClive WellerPublished in: Clinical and translational medicine (2023)
Emerging picture is of (i) clinical phenotype being described by deficits in microbial metabolites essential to gut health; (ii) intestinal inflammation; (iii) a systemic inflammatory response syndrome.