Serum glucose, lactate dehydrogenase and hypertension are mediators of the effect of body mass index on severity of COVID-19.

Huadong YanAmrita VijayFanrong JiangNanhong ZhengYaoren HuHonghua YeBenjamin OllivereTing CaiAna M ValdesGuruprasad P Aithal

Published in: Endocrinology, diabetes & metabolism (2021)

Our data indicate that a larger proportion of the effect of BMI on severity of COVID-19 is mediated by glycemia and LDH levels whereas less than half of it is mediated by systemic inflammation.

Keyphrases

body mass index
coronavirus disease
sars cov
blood pressure
weight gain
physical activity
electronic health record
blood glucose
type diabetes
big data
adipose tissue
deep learning
artificial intelligence
insulin resistance