KRT17 Promotes the Activation of HSCs via EMT in Liver Fibrosis.

Jing ChenSi-Jia GeHai-Juan FengShu-Zhen WuRan JiWei-Rong HuangWei Huang Cui-Hua Lu

Published in: Journal of clinical and translational hepatology (2021)

KRT17 promoted HSC activation, proliferation and EMT in hepatic fibrosis probably via TGF-β1 signaling, and KRT17 might serve as a therapeutic target for the treatment of liver fibrosis.

Keyphrases

liver fibrosis
epithelial mesenchymal transition
transforming growth factor
signaling pathway
replacement therapy