Identification of cancer-related genes FGFR2 and CEBPB in choledochal cyst via RNA sequencing of patient-derived liver organoids.

Yongqin YeVincent Chi Hang LuiRosana Ottakandathil BabuZhongluan WuWeifang WuPatrick Ho Yu ChungKenneth Kak Yuen WongBin WangPaul Kwong Hang Tam

Published in: PloS one (2023)

The study identified dysregulated genes related to cancer pathways in CC patients suggesting cancer risk. The findings suggest that the elevated expression of FGFR2 and CEBPB in liver may contribute to cancer development in CC patients.

Keyphrases

end stage renal disease
papillary thyroid
ejection fraction
newly diagnosed
squamous cell
chronic kidney disease
peritoneal dialysis
squamous cell carcinoma
prognostic factors
patient reported outcomes
single cell
transcription factor
genome wide
patient reported
long non coding rna