circPDE4B prevents articular cartilage degeneration and promotes repair by acting as a scaffold for RIC8A and MID1.
Shuying ShenYute YangPanyang ShenJun MaBin FangQingxin WangKefan WangPeihua ShiShunwu FanXiang-Qian FangPublished in: Annals of the rheumatic diseases (2021)
This work highlights the function of the circPDE4B-RIC8A axis in OA joints, as well as its regulation of MAPK-p38, suggesting this axis as a potential therapeutic target for OA.