Glomerulocapillary miRNA response to HLA-class I antibody in vitro and in vivo.
Falko M HeinemannPeter T JindraClemens L BockmeyerPhilip ZeuschnerJuliane WittigHeike HöflichMarc EßerMahmoud AbbasGeorg DieplingerKatharina StolleUdo VesterPeter F HoyerStephan ImmenschuhAndreas HeinoldPeter A HornWentian LiUte EisenbergerJan U BeckerPublished in: Scientific reports (2017)
A random forest analysis based on glomerular miRNAs identified 18/20 DSA+ and 8/10 controls correctly. This glomerulocapillary miRNA signature associated with HLA class I-DSA could improve our understanding of ABMR and be useful for diagnostic or therapeutic purposes.