Cartilage Oligomeric Matrix Protein-Derived Peptides Secreted by Cartilage Do Not Induce Responses Commonly Observed during Osteoarthritis.

Enrique Andres Sastre Frank ZauckeJanneke Witte-BoumaGerjo J V M van OschEric Farrell

Published in: Cartilage (2020)

The 3 peptides tested do not regulate TGF-β signaling, angiogenesis and vascular tube formation, or synovial inflammation in vitro and therefore most likely do not play a major role in the disease process.

Keyphrases

amino acid
extracellular matrix
oxidative stress
rheumatoid arthritis
endothelial cells
transforming growth factor
vascular endothelial growth factor
knee osteoarthritis
protein protein
binding protein
wound healing