Tissue-Specific Oxidative Stress Modulation by Exercise: A Comparison between MICT and HIIT in an Obese Rat Model.
Carole GroussardFlorie MaillardEmilie VazeilleNicolas BarnichPascal SirventYolanda F OteroLydie CombaretElise MadeufAntoine SourdrilleGeoffroy DelcrosMonique EtienneAllison TeixeiraPierre SauvanetVincent PialouxNathalie BoisseauPublished in: Oxidative medicine and cellular longevity (2019)
Both HIIT and MICT improved the pro/antioxidant status. However, HIIT was more efficient than MICT in the skeletal muscle, whereas MICT was more efficient in epididymal adipose tissue. This suggests that oxidative stress responses to HIIT and MICT are tissue-specific. This could result in ROS generation via different pathways in these tissues. From a practical point of view, the two training modalities should be combined to obtain a global response in people with obesity.
Keyphrases
- high intensity
- adipose tissue
- insulin resistance
- oxidative stress
- skeletal muscle
- weight loss
- metabolic syndrome
- resistance training
- type diabetes
- dna damage
- anti inflammatory
- high fat diet
- gene expression
- cell death
- physical activity
- ischemia reperfusion injury
- high fat diet induced
- bariatric surgery
- induced apoptosis
- reactive oxygen species
- obese patients
- virtual reality