Cardiac structure, function, and coronary anatomy 10 years after isolated contemporary adjuvant radiotherapy in breast cancer patients with low cardiovascular baseline risk.
Pauline KrugXavier GeetsMartine BerlièreFrançois DuhouxChristophe BeauloyeAgnès PasquetDavid VancraeynestAnne-Catherine PouleurBernhard L GerberPublished in: European heart journal. Cardiovascular Imaging (2024)
Aside from minor alterations of regional strains and diastolic parameters, women who received isolated RT for BC had low prevalence of coronary disease, normal global systolic function, NT-proBNP, and exercise capacity and showed no structural changes by CMR, refuting significant long-term cardiotoxicity in such low-risk patients.
Keyphrases
- left ventricular
- ejection fraction
- coronary artery disease
- blood pressure
- end stage renal disease
- coronary artery
- early stage
- aortic stenosis
- chronic kidney disease
- newly diagnosed
- heart failure
- prognostic factors
- physical activity
- risk factors
- radiation therapy
- high intensity
- polycystic ovary syndrome
- squamous cell carcinoma
- adipose tissue
- aortic valve
- body composition
- patient reported
- breast cancer risk
- cervical cancer screening