Login / Signup

Chordoma of the sacrum of an adult naked mole-rat.

Jordan E ColeJames C SteeilSteven J SarroKenton L KernsAndrew Cartoceti
Published in: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc (2019)
The naked mole-rat (NMR; Heterocephalus glaber)-a small, eusocial, subterranean rodent native to East Africa-is distinguished by its capability to live long and resist changes associated with the aging process. Notably, a growing amount of research has been dedicated to NMRs' multifactorial capacity to resist cancer. Since 2016, however, zoos have begun to document various neoplasms in a handful of individuals. We present herein radiographic, gross anatomic, and histopathologic features of a case of a sacral chordoma in a geriatric female. Chordomas originate in notochordal remnants. These spinal tumors are most commonly seen in ferrets; chordomas are rare in humans, can be difficult to treat, and need wide surgical margins.
Keyphrases
  • oxidative stress
  • papillary thyroid
  • spinal cord
  • magnetic resonance
  • high resolution
  • squamous cell carcinoma
  • mass spectrometry
  • solid state
  • lymph node metastasis
  • spinal cord injury