Treatment outcomes of acute bipolar depressive episode with psychosis.
Marco Antonio CaldieraroSteven DufourLouisa G SylviaKeming GaoTerence A KetterWilliam V BoboSamantha WalshJessica JanosMauricio TohenNoreen A Reilly-HarringtonSusan L McElroyRichard C SheltonCharles L BowdenThilo DeckersbachAndrew A NierenbergPublished in: Depression and anxiety (2018)
Bipolar depressive episodes with psychotic features are more severe, and compared to nonpsychotic depressions, present a similar course of improvement. Given the small number of participants presenting psychosis, the lack of statistically significant difference between lithium- and quetiapine-based treatment of psychotic bipolar depressive episodes needs replication in a larger sample.