Weight Cycling and Knee Joint Degeneration in Individuals with Overweight or Obesity: Four-Year Magnetic Resonance Imaging Data from the Osteoarthritis Initiative.
Gabby B JosephSara RamezanpourCharles E McCullochMichael C NevittJohn LynchNancy E LaneValentina PedoiaSharmila MajumdarThomas M LinkPublished in: Obesity (Silver Spring, Md.) (2021)
Although participants' intent for weight cycling in this study was unknown, weight cyclers had significantly greater increases in cartilage and bone-marrow abnormalities over 4 years than noncyclers, independent of weight gain and loss.
Keyphrases
- weight gain
- body mass index
- birth weight
- weight loss
- magnetic resonance imaging
- bone marrow
- high intensity
- mesenchymal stem cells
- computed tomography
- rheumatoid arthritis
- quality improvement
- type diabetes
- physical activity
- insulin resistance
- electronic health record
- knee osteoarthritis
- machine learning
- magnetic resonance
- skeletal muscle
- adipose tissue
- diffusion weighted imaging