Association Between Homologous Recombination Repair Biomarkers and Survival in Patients With Solid Tumors.
Changxia ShaoYixin RenHeng ZhouCai ChenElisha J DettmanLiam C LeeRazvan CristescuAlexander GozmanFan JinWei ZhouPublished in: JCO precision oncology (2023)
This large, real-world study found no association between OS and either BRCA or HRR status but identified a possible linkage between HRD positivity and shorter median OS in patients with advanced solid tumors who did not receive PARPi or immunotherapy.