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Association Between Homologous Recombination Repair Biomarkers and Survival in Patients With Solid Tumors.

Changxia ShaoYixin RenHeng ZhouCai ChenElisha J DettmanLiam C LeeRazvan CristescuAlexander GozmanFan JinWei Zhou
Published in: JCO precision oncology (2023)
This large, real-world study found no association between OS and either BRCA or HRR status but identified a possible linkage between HRD positivity and shorter median OS in patients with advanced solid tumors who did not receive PARPi or immunotherapy.
Keyphrases
  • dna repair
  • dna damage
  • genome wide
  • free survival