Associations between Education Years and Resting-state Functional Connectivity Modulated by APOE ε4 Carrier Status in Cognitively Normal Older Adults.
Jiwon KimSunghwan KimYoo Hyun UmSheng-Min WangRegina Eun Young KimYeong Sim ChoeJiyeon LeeDonghyeon KimHyun Kook LimChang Uk LeeDong Woo KangPublished in: Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology (2023)
ε4 carriers, higher years of education were associated with higher rFC of the AD vulnerable network, but this contributed to lower cognitive function. These results contribute to a deeper understanding of the impact of cognitive reserve on sensitive functional intermediate phenotypic markers in the preclinical phase of AD.