An explorative approach to understanding individual differences in driving performance and neurocognition in long-term benzodiazepine users.
Frederick R J VinckenboschAnnemiek VermeerenEric F P M VuurmanNick N J J M van der SluiszenJoris C VersterAurora J A E van de LooJoke H van DijkenJanet L VeldstraKarel A BrookhuisDick De WaardJohannes G RamaekersPublished in: Human psychopharmacology (2021)
Functional impairments in long-term BZRA users are not attributable to self-reported clinical complaints or estimated BZRA concentrations, except for road-tracking, which was impaired in CBZRA + users. Limitations to address are the lack of assessment of objective clinical complaints, acute task related stress, and actual BZRA plasma concentrations. In conclusion, the results confirm previous findings that demonstrate inferior performance across several psychomotor and neurocognitive domains in long-term BZRA users.