Bipolar symptoms, somatic burden, and functioning in older-age bipolar disorder: Analyses from the Global Aging & Geriatric Experiments in Bipolar Disorder Database project.

Jennifer B Levin Annemieke Dols Soham Rej Osvaldo P Almeida Alexandra J M Beunders Hilary P BlumbergFarren B S BriggsBrent P ForesterRegan E PatrickOrestes V ForlenzaAriel G GildengersEsther JimenezEduard VietaBenoit MulsantSigfried N T M SchouwsNadine PaansSergio A StrejilevichAshley SutherlandShang-Ying TsaiBetsy WilsonLisa T Eyler

Published in: Bipolar disorders (2021)

Findings suggest an attenuation of BD symptoms in OABD, despite extensive somatic burden. Depressive symptom severity was strongly associated with worse functioning in older individuals, underscoring the need for effective treatments of BD depression in older people. This international collaboration lays a path for the development of a better understanding of aging in BD.

Keyphrases

bipolar disorder
major depressive disorder
sleep quality
community dwelling
middle aged
physical activity
copy number
depressive symptoms
risk factors
adverse drug
dna methylation
hip fracture