A reduced dose of fluconazole as primary antifungal prophylaxis is not associated with increased risk of invasive fungal infections after allogeneic stem cell transplantation from a HLA identical sibling.

Barbara SarinaJacopo MariottiStefania BramantiLucio MorabitoRoberto CrocchioloAndrea RimondoFederica TordatoDaria PocaterraErminia CasariChiara De PhilippisCarmelo Carlo-StellaArmando SantoroLuca Castagna

Published in: Transplant infectious disease : an official journal of the Transplantation Society (2018)

In summary, fungal prophylaxis with fluconazole 100 mg/d results in very low incidence of PP-IFI, GVHD and NRM in low-risk allo-SCT.

Keyphrases

stem cell transplantation
candida albicans
high dose
risk factors
allogeneic hematopoietic stem cell transplantation
low dose
acute myeloid leukemia
acute lymphoblastic leukemia
hematopoietic stem cell