Development of a NanoString assay to detect leukemogenic fusion transcripts in acute myeloid leukemia.
Dong HuW ZhouF WangS M ShuL L FanJ HeP WangY L HeW DuJ H ZhangJ X DuanL SunJ ZhengX Q LiH Y LiX L FengS A HuangPublished in: International journal of laboratory hematology (2016)
NanoString can serve as a reliable and alternative molecular method to multiplexed RT-PCR for diagnosis of de novo AML with the perspective of screening/quantitation of a large number of leukemogenic fusion transcripts and prognostic genes. However, NanoString may not be an alternative method for monitoring minimal residual disease in AML.