Effect of ET-A blockade on portal pressure and hepatic arterial perfusion in patients with cirrhosis: A proof of concept study.
Alexander ZipprichFleur GittingerMatthias WinklerMatthias M DollingerCristina RipollPublished in: Liver international : official journal of the International Association for the Study of the Liver (2021)
Administration of a selective ET-A antagonist decreases the portal pressure in cirrhotic patients. This decrease was higher in CP B patients and the non-responders showed a higher increase in hepatic arterial flow. Selective ET-A antagonists might be a future treatment option in patients with portal hypertension.