Whole-body MRI evaluation in neurofibromatosis type 1 patients younger than 3 years old and the genetic contribution to disease progression.
Eungu KangYoon-Myung KimYunha ChoiYena LeeJunYoung KimIn Hee ChoiHan-Wook YooHee Mang YoonBeom-Hee LeePublished in: Orphanet journal of rare diseases (2022)
WBMRI provides important information for the clinical care for young pediatric NF1 patients. As NF1 progresses in even these young patients, and is related to family history and the affected NF1 domains, serial evaluation with WBMRI should be assessed based on the clinical and genetic features for the patients' best care.
Keyphrases
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- healthcare
- peritoneal dialysis
- signaling pathway
- prognostic factors
- magnetic resonance imaging
- gene expression
- immune response
- oxidative stress
- cell proliferation
- computed tomography
- lps induced
- young adults
- patient reported outcomes
- chronic pain
- nuclear factor
- health insurance