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Integrative transcriptome analysis of malignant pleural mesothelioma reveals a clinically relevant immune-based classification.

Ania AlayDavid CorderoSara Hijazo-PecheroElisabet AliagasAdriana Lopez-DorigaRaúl MarínRamón PalmeroRoger LlatjósIgnacio EscobarRicard RamosSusana PadronesVíctor MorenoErnest NadalXavier Solé
Published in: Journal for immunotherapy of cancer (2021)
This study identifies a novel immune-based signature with potential clinical relevance based on TH2 and TC levels, unveiling a fraction of patients with MPM with better prognosis and who might benefit from immune-based therapies. Molecular specificities of the different groups might be used to tailor specific potential therapies in the future.
Keyphrases
  • machine learning
  • deep learning
  • genome wide
  • human health
  • gene expression
  • current status
  • single molecule
  • climate change