Storage differentially impacts alloimmunization to distinct red cell antigens following transfusion in mice.
Cheryl L MaierRyan P JajoskySeema R PatelHans P VerkerkeMegan D FullerJerry William AllenPatricia E ZerraRoss M FasanoSatheesh ChonatCassandra D JosephsonDavid R GibbStephanie C EisenbarthC John LuckeyKrystalyn E HudsonJeanne E HendricksonConnie M ArthurSean R StowellPublished in: Transfusion (2023)
These data demonstrate a dichotomous impact of storage on immunization to distinct RBC antigens, offering a possible explanation for inconsistent clinical experience and the need for additional studies on the relationship between RBC storage and alloimmunization.