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Storage differentially impacts alloimmunization to distinct red cell antigens following transfusion in mice.

Cheryl L MaierRyan P JajoskySeema R PatelHans P VerkerkeMegan D FullerJerry William AllenPatricia E ZerraRoss M FasanoSatheesh ChonatCassandra D JosephsonDavid R GibbStephanie C EisenbarthC John LuckeyKrystalyn E HudsonJeanne E HendricksonConnie M ArthurSean R Stowell
Published in: Transfusion (2023)
These data demonstrate a dichotomous impact of storage on immunization to distinct RBC antigens, offering a possible explanation for inconsistent clinical experience and the need for additional studies on the relationship between RBC storage and alloimmunization.
Keyphrases
  • sickle cell disease
  • dendritic cells
  • single cell
  • red blood cell
  • cell therapy
  • electronic health record
  • type diabetes
  • adipose tissue
  • machine learning
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  • artificial intelligence