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Loss of ciliary zonule protein hydroxylation and lens stability as a predicted consequence of biallelic ASPH variation.

Owen M SiggsEmmanuelle SouzeauJamie E Craig
Published in: Ophthalmic genetics (2019)
Our results implicate ASPH-mediated hydroxylation in the formation of FBN1/LTBP2 microfibril bundles and competent ciliary zonules.
Keyphrases
  • intellectual disability
  • protein protein
  • binding protein