Thromboprophylaxis in COVID-19: Weight and severity adjusted intensified dosing.

Matthias M Engelen Christophe Vandenbriele Valérie Spalart Caroline P Martens Bert Vandenberk Pieter Sinonquel Natalie Lorent Paul De Munter Rik Willems Joost Wauters Alexander Wilmer Dieter Frans Dauwe Jan GunstIpek GulerStefan P Janssens Kimberly MartinodGriet PietersKathelijne PeerlinckPeter Verhamme Thomas Vanassche

Published in: Research and practice in thrombosis and haemostasis (2022)

In hospitalized patients with COVID-19, there were no additional symptomatic VTEs and a reduction in incidental deep vein thrombosis after implementing systematic thromboprophylaxis with weight-adjusted prophylactic (ward) to intermediate (ICU), but not therapeutic dosed anticoagulation. This intensified thromboprophylaxis was associated with a lower risk of major bleeding compared with therapeutic dosed anticoagulation.

Keyphrases

venous thromboembolism
direct oral anticoagulants
atrial fibrillation
body mass index
weight loss
coronavirus disease
physical activity
sars cov
weight gain
intensive care unit
body weight
acute respiratory distress syndrome
extracorporeal membrane oxygenation