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Sex-dependent selection, ageing, and implications for "staying alive".

Robert C BrooksKhandis R Blake
Published in: The Behavioral and brain sciences (2022)
Incorporating theoretic insights from ageing biology could advance the "staying alive" hypothesis. Higher male extrinsic mortality can weaken selection against ageing-related diseases and self-preservation, leading to high male intrinsic mortality. This may incidentally result in female-biased longevity-promoting traits, a possibility that will require rigorous testing in order to disentangle from the adaptive self-preservation hypothesis presented in the target article.
Keyphrases
  • cardiovascular events
  • genome wide
  • type diabetes
  • cardiovascular disease
  • gene expression
  • coronary artery disease
  • drosophila melanogaster
  • drug induced